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TEMPE, Ariz. (AP) — The Arizona Cardinals will be without two starters — and probably a third — when they try to stay unbeaten Sunday in a road game against the Cleveland Browns.

Cardinals coach Kliff Kingsbury confirmed tight end Maxx Williams is out for the season because of a right knee injury he suffered last week in the team’s 17-10 victory over the San Francisco 49ers.

He also said three-time Pro Bowl center Rodney Hudson (ribs) will miss the Browns game, while linebacker Chandler Jones is doubtful after testing positive for COVID-19 on Tuesday.

Kingsbury said Jones was experiencing symptoms and it “would be a stretch” to expect the linebacker to return in time for the Browns game.

The 31-year-old Jones has been is one of the league’s elite pass rushers and was the Week 1 NFC Defensive Player of the Week after a five-sack performance against the Tennessee Titans.

“That’s just the way it goes,” Kingsbury said. “We’ve been fully vaccinated now for a while. It’s unfortunate, particularly for Chandler, who was really playing at a high level. Hopefully he can get well rested and be back by next week’s game so we’ll see how it plays out.”

The Cardinals have a 5-0 record for the first time since 1974 and feature one of the NFL’s best offenses. The 6-foot-4, 252-pound Williams had been a big part of that and was on pace for a career year with 193 yards receiving through five games.

Williams was injured after his right knee buckled at the end of the run that resulted in a 14-yard reception.

“I just think guys have to step up,” Cardinals quarterback Kyler Murray said. “Guys who have been maybe waiting for an opportunity to show their skills, I think when a guy goes down, it’s an opportunity to step up and kind of make those plays and fill that void.”

Hudson was one of Cardinals’ key offseason signings after coming from the Las Vegas Raiders. The 11-year veteran has quickly turned into a team leader in Arizona with teammates and coaches raving about his physical and mental talent.

“I’m not sure if you can replace him as far as helping the plays being effective,” Kingsbury said. “He was such a great presence for us in the pass protection and the run game. It’s hard to account for not having him in there.”

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Bridgewater, Beckham playing as Broncos visit Browns

CLEVELAND (AP) — Broncos quarterback Teddy Bridgewater and Browns wide receiver Odell Beckham Jr. are both active and will play Thursday night despite being slowed by injuries.

Bridgewater was listed as questionable this week with a foot injury sustained last week against Las Vegas when he got stepped on by a teammate. A quadriceps injury was added for Bridgewater to the Broncos’ final injury report Wednesday.

Denver starting left tackle Garett Bolles (knee) will play as well.

Beckham was questionable after injuring his right shoulder last week in a loss to Arizona. He didn’t practice this week.

Beckham’s return should help the injury-ravaged Browns (3-3), who enter a critical game extremely short-handed.

Quarterback Baker Mayfield is out with a left shoulder injury, ending his streak of 53 consecutive starts and raising questions about his health for the remainder of the season. Case Keenum will start in his place.

Mayfield has a torn labrum in his non-throwing shoulder and is hoping rest will reduce the inflammation and allow him to return on Oct. 31 against Pittsburgh.

Cleveland also is without running backs Nick Chubb and Kareem Hunt due to calf injuries. Hunt is on injured reserve and will be sidelined at least two more games.

Browns starting right tackle Jack Conklin will miss his second game in a row with a knee injury. Left tackle Jedrick Wills Jr. is back after missing the past two games with an ankle sprain suffered in Week 1.

The beat-up Browns did get some good news as wide receiver Jarvis Landry was activated from injured reserve hours before the game after he sat out four weeks with a sprained medial collateral ligament.

Landry is considered the heart and soul of Cleveland’s team. His return will give Keenum, who is making his first start since 2019 with Washington, a needed playmaker and bring comfort to coach Kevin Stefanski.

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More AP NFL: https://apnews.com/hub/NFL and https://twitter.com/AP_NFL

Copyright © 2021 The Associated Press. All rights reserved. This material may not be published, broadcast, written or redistributed.

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