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Panthers running back Christian McCaffrey did not practice Thursday, a sign that he could miss his third straight game while trying to rehab from a hamstring injury.

The 2019 All-Pro running back had participated in four straight practices for the Panthers on a limited basis.

Coach Matt Rhule told reporters on Wednesday that McCaffrey was “50-50” for the game and that his playing status would likely come down to a game-time decision.

Rhule does not address reporters on Thursday of a normal game week.

The Panthers (3-2) host the Minnesota Vikings (2-3) on Sunday.

The Panthers’ 2017 first-round draft pick was injured in a Week 3 win against the Houston Texans. He hasn’t played since and the Panthers are 0-2 without him in the starting lineup after starting the season 3-0.

Chuba Hubbard would start if McCaffrey can’t play. Hubbard ran for 101 yards on 24 carries in Carolina’s 21-18 loss to the Philadelphia Eagles last Sunday.

The Panthers also placed punter Joe Charlton on injured reserve with back soreness and signed Ryan Winslow to the practice squad.

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How long is Russell Wilson out? Injury timeline, return date, latest updates on Seahawks QB

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It might take a little getting used to, but there'll be a new look at quarterback in Seattle for the first time in nearly a decade.

Dating back to Sept. 9, 2012, it's been 149 games since a quarterback other than Russell Wilson started a game for the Seahawks, but now with an injury to Wilson, Geno Smith will start the team's Week 6 game against the Steelers on Sunday night.

Wilson sustained a hand injury last week against the Rams in the Seahawks' 26-17 loss. He went 11-for-16 with 152 yards and one touchdown and interception apiece before being replaced by Smith. The injury was also the first significant one Wilson has sustained over the course of his career.

He had surgery on his hand last week, but made a quick return to practice.

Lion Heart. pic.twitter.com/rgKNk7Qit5

— Russell Wilson (@DangeRussWilson) October 9, 2021

Russell Wilson a limited practice participant six days after surgery, cuz, ya' know...

Chris Carson does not practice. Neck is a real issue. DK Metcalf's foot pain keeps him out. Bobby Wagner, Damien Lewis return on a limited basis. #Seahawks

— Gregg Bell (@gbellseattle) October 14, 2021

There are also reports that Wilson partook in practice by using his left, non-dominant hand.

The fact that Wilson returned to practice in any fashion just six days after surgery is remarkable, but coach Pete Carroll hedged his bets and played it safe, placing Wilson on injured reserve, making him eligible to return as early as Week 10 when the Seahawks take on the Packers.

Here's everything else you need to know about his injury.

MORE: Where will Russell Wilson play in 2022?

How long will Russell Wilson be out?

As of now, Wilson will miss at least the next three games, though at first Seahawks coach Pete Carroll was initially unsure of how serious Wilson's injury was.

He also offered some interesting praise of the seven-time Pro-Bowl quarterback.

"Russell's one of the great healers of all time and he'll do whatever he can to get back as soon as absolutely possible," Carroll said after the game against the Rams where Wilson got hurt.

When the injury first happened, the initial reports were much worse, with some NFL insiders believing Wilson would miss over a month.

More on Seattle Seahawks QB Russell Wilson having surgery on his injured finger and being sidelined 6-8 weeks:https://t.co/y1SAtRJuzk

— Adam Schefter (@AdamSchefter) October 9, 2021

The three week timeline for Wilson's return is simply the minimum, so he could miss more than that, but Carroll and Wilson were both optimistic.

MORE: Geno Smith NFL career timeline

What is Russell Wilson's injury?

Originally thought to be a badly sprained finger by coach Pete Carroll, Wilson actually suffered two more serious injuries.

Statement regarding @Seahawks QB @DangeRussWilson: pic.twitter.com/kR9X37fzJ6

— Seahawks PR (@seahawksPR) October 9, 2021

Wilson “sustained two injuries to the finger: an extensor tendon rupture (mallet finger) and a comminuted fracture-dislocation of the proximal interphalangeal joint,” the statement from the Seahawks read. He also had his finger stabilized with screws, as a simple splint wouldn't have been enough to heal his finger.

I'm sure it's fine pic.twitter.com/6yUUb3zok2

— Internet #BlackLivesMatter (@cjzero) October 8, 2021 Russell Wilson injury timeline

Oct. 7, 2021: Wilson and the Seahawks were playing the Rams on 'Thursday Night Football' when Wilson tried to throw a pass late in the third quarter before the Rams' Aaron Donald took a swing at it and blocked it. That play was the one that led to Wilson's injury. He stayed in for a few drives after that but was then replaced by Geno Smith to start the fourth quarter.

Russell Wilson’s finger ????

pic.twitter.com/9sY6wWbjMp

— PFF (@PFF) October 8, 2021

Oct. 9, 2021: Wilson had surgery on his finger, performed by hand specialist Steven Shin at Los Angeles' Cedars Sinai hospital.

"“Based on what I saw today, I am fully confident Russell will return to the NFL this season and play at the same world-class level that fans have come to expect of one the game’s very best quarterbacks,” Shin said in a statement.

Oct: 14-15, 2021: Just six days after major surgery, Wilson returned to Seahawks' practice as a limited participant. He was there mainly to help Geno Smith step into the starting role and get comfortable with everything, but he took some time to show off, too, throwing passes with his left (non-dominant) hand.

Oct. 15, 2021: Seahawks coach Pete Carroll officially places Wilson on injured reserve, setting him up to miss at least the next three games. The earliest he can return is Week 10 against the Packers.

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